Interesting research on how to get people motivated to be more active and perhaps exercise more. Telegraph reports, "In tests, very overweight mice doubled their amount of physical activity when the hormone leptin – which regulates appetite – was switched on in their brain. Scientists hope to build on the research to create medication to help people who suffer from obesity to lead more active lives. Dr Christian Bjorbaek, an endocrinologist Harvard Medical School, Massachusetts, said: "This gives us the opportunity to search for drugs that might induce the desire or will to voluntarily exercise."